Immunology

Jordan Hamilton is a brilliant immunologist who works at a major teaching hospital in Sacramento, California. When a young woman dies during a routine operation to remove her ruptured breast implants, Jordan realizes that the victim reacted to a deadly element in silicone. Women are dying and Jordan is determined to find the explanation.
A whirlwind tale of power, medicine, politics, and greed, this fast-paced thriller explores the seedier side of medicine, from a prestigious hospital to a sordid front for drug distribution.

Janeway’s Immunobiology is a textbook that introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.

Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout—that of the host’s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.

Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.

New in the Eighth Edition

• Innate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook.  Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes).
• The section on complement has been reworked and reconceived—explaining the lectin pathway first—making it easier to teach by placing it into the context of innate recognition.
• Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms.
• The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book.
• Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen.
• Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria.
• Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways.
• Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines.
• Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text.
• The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways.
• New references have been added throughout the text.
  

An exceptionally lucid guide to the latest immunology concepts! Through five best-selling editions, readers worldwide have appreciated this book's in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource!

• Clearly explains the experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels-and the conclusions that can be drawn from those observations.
• Highlights the implications of immunologic science for the management of human disease, emphasizing the clinical relevance of the material.

• Innate immunity chapter has been increased and moved to the beginning of the book to reflect how this area is newly recognized as a critical part of immunology.
• New material has been added on:
  - recognition of microbial products by cytoplasmic and membrane sensors
  - intricate organization of lymphoid tissues
  - functional heterogeneity of subsets of dendritic cells and lymphocytes
  - roles of regulatory cells and inhibitory pathways in immune regulation.
  
• Provides a wealth of excellent full-color photographs and illustrations that enable you to visualize immunologic processes quickly.
• Includes highlighted "take-home messages" that make it easy to review key information.
• Image Collection on Evolve

MAXIMUM RETENTION--MINIMAL TIME

"I wish I had a copy of this book during my microbiology course ... excellent for classroom studies during the first two years of medical school." -- Judy Vu, Third Year Medical Student, University of Utah School of Medicine

"I really enjoyed 'pimping' friends with questions from this book as a review for Step 1." -- Pete Pelletier, Third Year Medical Student, University of Utah School of Medicine

"This excellent book covers the material second year medical students need to study for exams. It could easily be used in a small group to review. 3 Stars."--Doody's Review Service

Deja Review: Microbiology and Immunology boils down your coursework to just the critical concepts you need to know for exam success. This unbeatable guide features a quick-read, two-column "flashcard" Q&A format--specifically designed to help you remember a large amount of pertinent information in the least amount of time possible. The format allows you to zero-in on only the correct answers to promote memory retention and get the most out of your study time. Great for last minute review of high-yield facts, Deja Review provides a straightforward way for you to assess your strengths and weaknesses so you can excel on your course exams and the USMLE Step 1.

• Active recall questions allow you to understand, not just memorize, the content
• Clinical vignettes at the end of chapters prepare you for board-style questions
• Portable size for study on the go--fits in your white coat pocket
• Bookmark included to guide you through easy-to-use flashcard presentation

The new edition of this popular text presents microbiology in a succinct, easy-to-use, and engaging manner. Clear discussions explain how microbes cause disease in humans, and review the updated vaccines and new antibiotics currently available to treat these diseases. Expert coverage of basic principles, the immune response, laboratory diagnosis, bacteriology, virology, mycology, and parasitology ensures that you'll understand all the facts vital to the practice of medicine today. A revised artwork program illustrates the appearance of disease, simplifying complex information, while text boxes and additional summary tables emphasize essential concepts and learning issues for more efficient exam review. Online access to Student Consult-where you'll find the complete contents of the book, fully searchable...Integration Links to bonus content in other Student Consult titles...updated features for both students and instructors...and much more-further enhances your study and exponentially boosts your reference power.

• Focuses on why the biologic properties of organisms are important to disease in humans, equipping you with a practical understanding of microbiology.
  
• Examines etiology, epidemiology, host defenses, identification, diagnosis, prevention, and control for each microbe in consistently organized chapters, enabling you to find the information you need fast.
  
• Features summary tables and text boxes that emphasize essential concepts and learning issues, enabling you to make your exam review more efficient.
  
• Correlates basic science with clinical practice through review questions at the end of each chapter to help you understand the clinical relevance of the organisms examined.
  
• Uses clinical cases from literature reports to illustrate the epidemiology, diagnosis, and treatment of infectious diseases.

• Features revised artwork-more than 635 brilliant images, nearly all in full color-that offers a more consistent and modern approach to the study of medical microbiology.
  
• Provides more clinical photographs throughout that help you better understand the clinical applications of microbiology.
  
• Offers expanded use of summary boxes for bacteria throughout all organism chapters to further enhance your review and learning.
  
• Includes enhanced Student Consult features including self-assessment questions, clinical cases, animations showing the actions of various important toxins, and a PowerPoint presentation with supplemental images of organisms and stains.

Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

From the foreword by Dr. Douglas Kerr, Director, Johns Hopkins Transverse Myelitis Center

"The Autoimmune Epidemic by Donna Jackson Nakazawa is an astounding book....It is the kind of book that will rivet you and scare you. It will make you angry. It will amaze you with the courage of some of the people described in the book...The Autoimmune Epidemic is every bit as compelling as Upton Sinclair's The Jungle...It is also every bit as necessary as An Inconvenient Truth....

You will leave this book with no reservations about the veracity of the conclusions: put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise. The research is sound. The conclusions unassailable....

Reading The Autoimmune Epidemic is a necessary first step. Reading The Autoimmune Epidemic is a life-altering event. It needs to be."

Part slave narrative, part memoir, and part sentimental fiction, Behind the Scenes depicts Elizabeth Keckley's years as a slave and subsequent four years in Abraham Lincoln's White House during the Civil War. As public drama privately experienced, Keckley's work presents Jefferson Davis and his wife, Abraham Lincoln and Mary Todd Lincoln, and even Stephen Douglas and "Mrs. Senator Douglas" in the foreground, with the war, and slavery as the issue that precipitated it, in the background. Through the eyes of this black woman--an ex-slave, seamstress, and dressmaker--we see a wide range of historical figures and events of the antebellum South, the Washington of the Civil War years, and the final stages of the war.

I love the way the book is organized. Wendy Miller, MS, CLS(NSA), MT(ASCP)SI I enthusiastically support the author s approach I think this is a very valuable text Stephen M. Johnson, MS, MT (ASCP) Completely updated to include new information about the immune system and new treatments for immunological diseases! This practical introduction to clinical immunology covers all of the essential theoretical principles and the serology techniques most commonly used in the laboratory. Structured into easy-to-read, student-friendly sections, the 3rd Edition focuses on the direct application of theory to clinical laboratory practice. With questions by Maribeth L. Flaws, Ph.D., SM(ASCP)SI, Rush University Medical Center, Chicago, Illinois and Christine Dorresteyn Stevens, EdD, MT(ASCP), Western Carolina University, Cullowhee, North Carolina